Matthias Sauerbruch studied at the Hochschule der Künste Berlin (Berlin University of the Arts) and the Architectural Association School of Architecture in London. Together with Louisa Hutton, he is a founding partner of the practice, which was established in London in 1989 and has centered its operations in Berlin from 1993. He has directed the office since its founding.

Matthias was a Unit Master at the Architectural Association School of Architecture in London and held tenure professorships at the Technical University of Berlin and the State Academy of Fine Arts in Stuttgart. His extensive academic career also included visiting professorships at the University of Virginia, Charlottesville, VA; the Harvard Graduate School of Design, Cambridge, MA; and the Berlin University of the Arts. His writings have been widely published, and he has given lectures worldwide at numerous academic and professional events. He has co-curated the exhibitions “Culture City” (2013), “Urbainable” (2020) in Berlin as well as “draw, love, build” in Mestre and in Berlin

As a founding member of the German Sustainable Building Council (DGNB), Matthias is deeply committed to promoting sustainable practices in architecture. Furthermore, he served on the Zurich Design Advisory Board for Architecture and Urban Design as well as the Urban Design Commission in Munich. He sits on the board of the KW Institute for Contemporary Art in Berlin. He is an honorary fellow of the American Institute of Architects and the Royal Institute of the Architects of Ireland (RIAI), and a member of the Architecture Section of the Academy of Arts in Berlin, of which he was director from 2018 to 2021.